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King's Year 2 BDS: Immunology · Meedu
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Dentistry
King's Year 2 BDS: Immunology
Introduction to Immunology
Adaptive Immunity: B-Cell Response
Adaptive Immunity: T-Cell Response
Immunodeficiency & HIV
Mechanisms of Autoimmunity & Hypersensitivity
Mucosal Immunity
King's Year 2 BDS: Immunology
Year 2 Immunology module at King's College London Dental Institute. Innate and adaptive immunity (B-cell and T-cell responses), immunodeficiency and HIV, autoimmunity, hypersensitivity, and mucosal immunity relevant to dental practice.
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A 32-year-old healthcare worker undergoes tuberculin skin testing (Mantoux test). At what point should the test site be formally read to determine a positive result, and why?
Select the correct answer
A.
Immediately after injection, as mast cell degranulation produces an instant wheal-and-flare response mediated by IgE
1
B.
At 2–4 hours post-injection, as complement activation and immune complex deposition produce early induration
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C.
At 12–24 hours post-injection, as neutrophil recruitment produces peak inflammation within the first day
3
D.
At 48–72 hours post-injection, as T-lymphocyte and macrophage infiltration produces induration through cell-mediated immunity
4
E.
At 7–10 days post-injection, as B-lymphocyte proliferation and antibody production require over a week to generate a measurable response
5
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